An xbox controller can be used on a PC, but it really depends on the game whether it's supported or not. Unfortunally, Bioshock 2 does not support it.

As a bonus, Valve says the Steam Controller was designed from the ground up “to be hackable”. The controller, along with Valve-built Steam Boxes, is due later this year. The controller will also work with any Steam version, including Steam for Mac. Anything but fighting games. Honestly even something like dark souls works well with the steam controller. In strategy games like Civ, TR and even blood bowl setting both pads as a mouse give you really awesome control over the mouse pointer.

See: I talked to the dev team about controller support for BioShock 2, and I want to let you know that we won’t be adding this into the game in a patch. The decision not to support the controller was not made lightly, and to add it now would take a complete re-envisioning of the UI that the team worked so hard to create. I’m sorry for those of you who are disappointed, and I want you to know that your comments and concerns have been heard and will be taken in to account when we are planning in the future. You can use ANY controller that works on a PC to play ANY game you want. Just get yourself a key mapping program. Xbox 360 controller, PS3 dualshock, any 3rd party gamepad, etc.

Plus, you can download a free trial if you’re not sure whether it’s for you. Best screen recording for chrome/mac. Of course, if you need more advanced editing tools for your screen captures, you’ll want to use Camtasia. You can even record audio with your video. And, there’s a free trial available if you want to try it. Snagit is another TechSmith product that I often use for screen captures, but what many people don’t know is that you can also use it to record a simple short video and share it in GIF or MPEG-4 format.

If your computer recognizes input from it, you can use it in games. I do it all the time bc I'm disabled and not physically able to use a mouse and keyboard at the same time. There are a couple of decent keymappers out there, but imo the best by FAR is Xpadder: which uses an intuitive GUI to walk you through setting up the controller to mimic any combination of keys mouse that you like. It's a shareware prog that costs $10, but it's worth every penny. It'll let you create complicated macros that include mouse movements, clicks, wait periods, key presses, holding down keys, etc. -- and then assign that macro to a single button on the controller. You can even assign different macros depending on how far you tilt the stick on your controller.

For example, you can set it up so that tilting the controller's left stick to less than 50% of its total range will mimic 'move the mouse forwards while holding down Shift and then press the R key,' but tilting the same stick to more than 50% of its range will be the same as 'click the left mouse button, wait two seconds, then quickly press the Y key three times in a row'. In short, you can make the controller do anything that can BE done with a mouse and keyboard, and it includes support for 'rumble' and for multiple controllers at the same time (for multiplayer games). You can even have it so that a single button or stick on the controller will mimic up to 10 different key mouse actions, so that you're not limited by the number of buttons on the controller, because it's possible to set a button to shift the whole controller over to config #2 where config #2 is an entirely different set of key mouse combos for each button. And no, I'm not affiliated with Xpadder in any way. Just a gamer who is incredibly thankful this program exists so that I'm able to enjoy PC games that would otherwise be off limits for someone with my limitations.